Annotation Detail

Information
Associated Genes
HSPA5
Associated Variants
HSPA5 UNDEREXPRESSION
Source Database
MMMP
Description
siRNA knockdown of GRP78 increased ER stress-induced caspase-4 activation and apoptosis
MMMP State
downregulated by
MMMP Molecule
GRP78
MMMP Molecule Alias
Glucose regulated protein 78
MMMP Modifier
GRP78 siRNA
MMMP Relationship
sensitivity to
MMMP Drug
Thapsigargin
MMMP Model
3
MMMP Reference
Jiang CC, Cancer Res 2007, 67:9750-61
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
ThapsigarginSensitivitytrue