Annotation Detail
Information
- Associated Genes
- PARP1
- Associated Variants
- PARP1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity
- MMMP State
- downregulated by
- MMMP Molecule
- PARP-1
- MMMP Molecule Alias
- Poly ADP-ribose polymerase 1
- MMMP Modifier
- PARP-1 siRNA
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 2
- MMMP Reference
- Tentori L, Eur J Cancer 2008, 44:1302-14
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Sensitivity | true |