Annotation Detail
Information
- Associated Genes
- TBX21
- Associated Variants
- TBX21 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- T-bet is essential for NK-mediated cross-talk between innate and adaptive immune responses to metastatic disease
- MMMP State
- downregulated by
- MMMP Molecule
- T-bet
- MMMP Modifier
- T-bet knockout
- MMMP Relationship
- resistance to
- MMMP Drug
- NK cell lysis (immunotherapy)
- MMMP Model
- 2
- MMMP Reference
- Werneck MB, J Immunol 2008, 180:8004-10
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| NK cell lysis (immunotherapy) | Resitance or Non-Reponse | true |