Annotation Detail
Information
- Associated Genes
- AMFR
- Associated Variants
- AMFR UNKNOWN
- Source Database
- MMMP
- Description
- Paclitaxel is selectively targeted to melanoma cells by AMF, which is the ligand of gp78 (which is overexpressed in malignant cells)
- MMMP State
- targeted by
- MMMP Molecule
- AMFR
- MMMP Molecule Alias
- Autocrine motility factor receptor, gp78
- MMMP Modifier
- AMF
- MMMP Modifier Alias
- Autocrine motility factor (phosphoglucose isomerase)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Paclitaxel
- MMMP Drug Alias
- Taxol
- MMMP Model
- 2
- MMMP Reference
- Kojic LD, PLoS One 2008, 3:e3597
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Paclitaxel | Sensitivity | true |