Annotation Detail
Information
- Associated Genes
- STAT3
- Associated Variants
- STAT3 UNKNOWN
- Source Database
- MMMP
- Description
- Defective activations of STAT3 Ser727 and PKC isoforms lead to oncostatin-M resistance in metastatic melanoma cells
- MMMP State
- phosphorylated (Ser-727)
- MMMP Molecule
- STAT3
- MMMP Molecule Alias
- Signal transducer and activator of transcription 3
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Oncostatin-M
- MMMP Drug Alias
- OSM
- MMMP Model
- 3
- MMMP Reference
- Lacreusette A, J Pathol 2009, 217:665-76
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Oncostatin-M | Sensitivity | true |