Annotation Detail

Information
Associated Genes
CFLAR
Associated Variants
CFLAR EXPRESSION
Source Database
MMMP
Description
Celastrol is a triterpene with anti-oxidant and anti-inflammatory properties. Celastrol-resistant B16F10 melanoma cells had a higher expression level of c-FLIP(L) and Snail as compared with a sensitive cell line
MMMP State
expressed
MMMP Molecule
FLIP
MMMP Molecule Alias
c-FLIP
MMMP Relationship
resistance to
MMMP Drug
Celastrol
MMMP Model
1
MMMP Reference
Kim Y, Biotechnol Lett 2009, 31:945-52
Drugs
Drug NameSensitivitySupported
CelastrolResitance or Non-Reponsetrue