Annotation Detail

Information
Associated Genes
STAT1
Associated Variants
STAT1 EXPRESSION
Source Database
MMMP
Description
STAT1-high tumor cells also demonstrate resistance to IFN-gamma (IFNg), ionizing radiation and doxorubicin relative to parental B16F1 and low expressors of the IFN/STAT1 pathway (STAT1-low genotype)
MMMP Drug
Radiotherapy
MMMP Model
2
MMMP State
expressed
MMMP Molecule
STAT1
MMMP Molecule Alias
Signal transducer and activator of transcription 1
MMMP Relationship
resistance to
MMMP Reference
Khodarev NN, PLoS One 2009, 4:e5821
Drugs
Drug NameSensitivitySupported
RadiotherapyResitance or Non-Reponsetrue