Annotation Detail
Information
- Associated Genes
- MAP2K1
- Associated Variants
- MAP2K1 P124L
- Source Database
- MMMP
- Description
- PLX 4720 is a BRAF inhibitor (MEK mutation causes cross-resistance to this drug)
- MMMP State
- mut P124L
- MMMP Molecule
- MEK1
- MMMP Relationship
- resistance to
- MMMP Drug
- PLX 4720
- MMMP Model
- 3
- MMMP Reference
- Emery CM, Proc Natl Acad Sci USA 2009, 106:20411-6
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| PLX 4720 | Resitance or Non-Reponse | true |