Annotation Detail

Information
Associated Genes
GSK3B
Associated Variants
GSK3B UNDEREXPRESSION
Source Database
MMMP
Description
Sorafenib: BRAF, CRAF, VEGFR and PDGFR inhibitor
MMMP State
downregulated by
MMMP Molecule
GSK3B
MMMP Modifier
GSK3B siRNA
MMMP Relationship
sensitivity to
MMMP Drug
Sorafenib
MMMP Drug Alias
Nexavar (R)
MMMP Model
3
MMMP Reference
Panka DJ, J Biol Chem 2008, 283:726-32
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
SorafenibSensitivitytrue