Annotation Detail

Information
Associated Genes
STAT3
Associated Variants
STAT3 UNDEREXPRESSION
Source Database
MMMP
Description
Targeting Stat3 in immune cells (hematopoietic system) can drastically improve CpG-based immunotherapeutic approaches
MMMP State
downregulated by
MMMP Molecule
STAT3
MMMP Molecule Alias
Signal transducer and activator of transcription 3
MMMP Modifier
STAT3 knockout
MMMP Relationship
sensitivity to
MMMP Drug
CpG oligonucleotide
MMMP Model
2
MMMP Reference
Kortylewski M, Cancer Res 2009, 69:2497-505
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
CpG oligonucleotideSensitivitytrue