Annotation Detail

Information
Associated Genes
SOX9
Associated Variants
SOX9 OVEREXPRESSION
Source Database
MMMP
Description
SOX9 is often downregulated in melanoma. Melanoma cell lines transfected with SOX9 (but not controls) are sensitive to retinoic acid
MMMP State
upregulated by
MMMP Molecule
SOX9
MMMP Modifier
SOX9 gene therapy
MMMP Relationship
sensitivity to
MMMP Drug
Retinoic acid
MMMP Model
3
MMMP Reference
Passeron T, J Clin Invest 2009, 119:954-63
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
Retinoic acidSensitivitytrue