Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF V600E
- Source Database
- MMMP
- Description
- Anti-melanoma efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAF(V600E) mutational status and sustained extracellular signal-regulated kinase (ERK) / mitogen-activated protein kinase (MAPK) pathway suppression
- MMMP State
- mut V600E
- MMMP Molecule
- BRAF
- MMMP Relationship
- sensitivity to
- MMMP Drug
- GDC-0879
- MMMP Drug Alias
- RAF inhibitor
- MMMP Model
- 4
- MMMP Reference
- Hoeflich KP, Cancer Res 2009, 69:3042-51
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| GDC-0879 | Sensitivity | true |