Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
- TP53 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Elafin is a protein that acts as a protease inhibitor; inhibition of p53 inhibits elafin anti-melanoma activity
- MMMP State
- inhibited by
- MMMP Molecule
- p53
- MMMP Molecule Alias
- TP53
- MMMP Modifier
- Pifithrin-alpha
- MMMP Modifier Alias
- QB102 (PFT-alpha)
- MMMP Relationship
- resistance to
- MMMP Drug
- Elafin
- MMMP Model
- 4
- MMMP Reference
- Yu KS, Int J Cancer 2009, Epub ahead of print
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Elafin | Resitance or Non-Reponse | true |