Annotation Detail
Information
- Associated Genes
- TNFRSF9
- Associated Variants
- TNFRSF9 OVEREXPRESSION
- Source Database
- MMMP
- Description
- NK cell depletion significantly reduced both tumor-specific CTL activity and the number of tumor-specific IFN-gamma-producing cells, suggesting that this synergistic effect requires the participation of both NK and CD8(+) T cells
- MMMP State
- activated by
- MMMP Molecule
- CD137
- MMMP Molecule Alias
- 4-1BB
- MMMP Modifier
- 4-1BB antibody (agonist)
- MMMP Modifier Alias
- CD137 antibody (agonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- IL-12
- MMMP Drug Alias
- Interleukin-12
- MMMP Model
- 2
- MMMP Reference
- Xu D, Int J Cancer 2004, 109:499-506
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| IL-12 | Sensitivity | true |