Annotation Detail
Information
- Associated Genes
- IFNAR1
- Associated Variants
- IFNAR1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- This phase II RCT showed that addition of IFN to bevacizumab was not associated with clinical benefit in patients with metastatic melanoma
- MMMP State
- activated by
- MMMP Molecule
- IFNAR
- MMMP Molecule Alias
- IFN alpha receptor
- MMMP Modifier
- IFN alpha
- MMMP Modifier Alias
- Interferon alpha
- MMMP Relationship
- no relationship with
- MMMP Drug
- Bevacizumab
- MMMP Drug Alias
- Avastin (R)
- MMMP Model
- 6
- MMMP Reference
- Varker KA, Ann Surg Oncol 2007, 14:2367-76
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Bevacizumab | Resitance or Non-Reponse | true |