Annotation Detail
Information
- Associated Genes
- IFNAR1
- Associated Variants
- IFNAR1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- In this phase II trial, no objective responses were noted; three patients demonstrated disease stabilization. This combination failed to demonstrate clinical efficacy in pretreated metastatic malignant melanoma
- MMMP State
- activated by
- MMMP Molecule
- IFNAR
- MMMP Molecule Alias
- IFN alpha receptor
- MMMP Modifier
- IFN alpha
- MMMP Modifier Alias
- Interferon alpha
- MMMP Relationship
- no relationship with
- MMMP Drug
- Thalidomide
- MMMP Model
- 5
- MMMP Reference
- Vaishampayan UN, Anticancer Drugs 2007, 18:1221-6
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Thalidomide | Resitance or Non-Reponse | true |