Annotation Detail

Information
Associated Genes
CD40
Associated Variants
CD40 OVEREXPRESSION
Source Database
MMMP
Description
Stimulation of CD40 and Toll-Like Receptors (TLR) can be synergistic, resulting in even stronger dendritic cell (DC) and CD8+ T cell responses and anticancer activity
MMMP State
activated by
MMMP Molecule
CD40
MMMP Molecule Alias
CD40L receptor
MMMP Modifier
CD40L gene therapy
MMMP Relationship
sensitivity to
MMMP Drug
CpG oligo + Poly(I:C)
MMMP Model
2
MMMP Reference
Stone GW, PLoS One 2009, 4:e7334
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
CpG oligo + Poly(I:C)Sensitivitytrue