Annotation Detail

Information
Associated Genes
IFNAR1
Associated Variants
IFNAR1 OVEREXPRESSION
Source Database
MMMP
Description
Activation of IFNAR and TLR3 shows synergistic therapeutic potential (inhibition of melanoma cell survival)
MMMP State
activated by
MMMP Molecule
IFNAR
MMMP Molecule Alias
IFN alpha receptor
MMMP Modifier
IFN alpha
MMMP Modifier Alias
Interferon alpha
MMMP Relationship
sensitivity to
MMMP Drug
Poly(I:C)
MMMP Drug Alias
TLR3 agonist
MMMP Model
3
MMMP Reference
Salaun B, Clin Cancer Res 2007, 13(15 Pt 1):4565-74
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
Poly(I:C)Sensitivitytrue