Annotation Detail

Information
Associated Genes
TLR3
Associated Variants
TLR3 OVEREXPRESSION
Source Database
MMMP
Description
Activation of IFNAR and TLR3 shows synergistic therapeutic potential (inhibition of melanoma cell survival)
MMMP State
activated by
MMMP Molecule
TLR3
MMMP Molecule Alias
Toll like receptor 3
MMMP Modifier
Poly(I:C)
MMMP Modifier Alias
Poly(inosine:cytosine)
MMMP Relationship
sensitivity to
MMMP Drug
IFN alpha
MMMP Model
3
MMMP Reference
Salaun B, Clin Cancer Res 2007, 13(15 Pt 1):4565-74
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
IFN alphaSensitivitytrue