Annotation Detail

Information
Associated Genes
CD28
Associated Variants
CD28 OVEREXPRESSION
Source Database
MMMP
Description
CD4+ T cells activated with anti-CD3 and anti-CD28 antibodies dramatically enhance chemotherapeutic melanoma responses in vitro and in vivo
MMMP State
activated by
MMMP Molecule
CD3, CD28
MMMP Modifier
CD3 and CD28 antibodies (activating)
MMMP Relationship
sensitivity to
MMMP Drug
Temozolomide
MMMP Drug Alias
TMZ
MMMP Model
4
MMMP Reference
Radfar S, J Immunol 2009, 183:6800-7
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
TemozolomideSensitivitytrue