Annotation Detail
Information
- Associated Genes
- ESR1
- Associated Variants
- ESR1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Combination of tamoxifen with CDDP was highly synergistic, whereas tamoxifen was antagonistic with carmustine and an activated form of dacarbazine
- MMMP State
- inhibited by
- MMMP Molecule
- Estrogen receptor
- MMMP Molecule Alias
- ESR1
- MMMP Modifier
- Tamoxifen
- MMMP Relationship
- resistance to
- MMMP Drug
- Dacarbazine
- MMMP Drug Alias
- DTIC
- MMMP Model
- 3
- MMMP Reference
- McClay EF, Cancer Res 1992, 52:6790-6
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Dacarbazine | Resitance or Non-Reponse | true |