Annotation Detail

Information
Associated Genes
TP53
Associated Variants
TP53 OVEREXPRESSION
Source Database
MMMP
Description
CP-31398 can stabilize wild-type p53 and rescue mutant p53 to enhance its transcriptional activity
MMMP State
activated by
MMMP Molecule
p53
MMMP Molecule Alias
TP53
MMMP Modifier
CP-31398
MMMP Relationship
no relationship with
MMMP Drug
Camptothecin
MMMP Model
3
MMMP Reference
Luu Y, Anticancer Res 2003, 23(1A):99-105
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
CamptothecinResitance or Non-Reponsetrue