Annotation Detail

Information
Associated Genes
IFNAR1
Associated Variants
IFNAR1 OVEREXPRESSION
Source Database
MMMP
Description
This drug combination works also in Bcl-2 or Mcl-1 expressing tumors
MMMP State
activated by
MMMP Molecule
IFNAR
MMMP Molecule Alias
IFN alpha receptor
MMMP Modifier
IFN alpha
MMMP Modifier Alias
Interferon alpha
MMMP Relationship
sensitivity to
MMMP Drug
Bortezomib
MMMP Drug Alias
Velcade (R)
MMMP Model
4
MMMP Reference
Lesinski GB, Cancer Res 2008, 68:8351-60
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
BortezomibSensitivitytrue