Annotation Detail

Information
Associated Genes
ESR1
Associated Variants
ESR1 UNDEREXPRESSION
Source Database
MMMP
Description
Meta-analysis of 6 trials involved a combined total of 912 patients. The findings demonstrated that tamoxifen does not improve the overall response rate, complete response rate, or survival rate when administered along with combined chemotherapy regimens
MMMP State
inhibited by
MMMP Molecule
Estrogen receptor
MMMP Molecule Alias
ESR1
MMMP Modifier
Tamoxifen
MMMP Relationship
no relationship with
MMMP Drug
Chemotherapy (miscellany)
MMMP Model
7
MMMP Reference
Lens MB, Cancer 2003, 98:1355-61
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
Chemotherapy (miscellany)Resitance or Non-Reponsetrue