Annotation Detail
Information
- Associated Genes
- TNFRSF9
- Associated Variants
- TNFRSF9 OVEREXPRESSION
- Source Database
- MMMP
- Description
- CTX creates an environment in which anti-4-1BB actively promotes the differentiation and expansion of tumor-specific CTLs
- MMMP State
- activated by
- MMMP Molecule
- CD137
- MMMP Molecule Alias
- 4-1BB
- MMMP Modifier
- 4-1BB antibody (agonist)
- MMMP Modifier Alias
- CD137 antibody (agonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Cyclophosphamide
- MMMP Drug Alias
- CTX
- MMMP Model
- 2
- MMMP Reference
- Kim YH, Mol Cancer Ther 2009, 8:469-78
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cyclophosphamide | Sensitivity | true |