Annotation Detail
Information
- Associated Genes
- IFNAR1
- Associated Variants
- IFNAR1 OVEREXPRESSION
- Source Database
- MMMP
- Description
- Metastatic human melanoma cells treated with IFN-beta plus mezerein (phorbol ester analog from the plant Daphne mezereum) undergo irreversible growth arrest and terminal differentiation followed by apoptosis, which is accompanied by downregulation of cell cycle related genes
- MMMP State
- activated by
- MMMP Molecule
- IFNAR
- MMMP Molecule Alias
- IFN alpha receptor
- MMMP Modifier
- IFN beta
- MMMP Modifier Alias
- Interferon beta
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Mezerein
- MMMP Model
- 3
- MMMP Reference
- Huynh KM, Gene 2009, 433:32-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Mezerein | Sensitivity | true |