Annotation Detail
Information
- Associated Genes
- ANPEP
- Associated Variants
- ANPEP UNKNOWN
- Source Database
- MMMP
- Description
- NGR peptide is a ligand for CD13, which is expressed by tumor vessels. NGR-TNF is a peptide-TNF conjugate able to target tumor blood vessels. EMAP-II sensitizes tumor vasculature to TNF
- MMMP Drug
- TNF + EMAP-II
- MMMP Model
- 2
- MMMP State
- targeted by
- MMMP Molecule
- CD13
- MMMP Molecule Alias
- Aminopeptidase N
- MMMP Modifier
- NGR peptide
- MMMP Relationship
- sensitivity to
- MMMP Reference
- Crippa L, Cancer Res. 2008 Feb 15;68(4):1154-61
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TNF + EMAP-II | Sensitivity | true |