Annotation Detail

Information
Associated Genes
ESR1
Associated Variants
ESR1 UNKNOWN
Source Database
MMMP
Description
In this phase III RCT of the combination of cisplatin, dacarbazine and carmustine with or without tamoxifen in patients with advanced malignant melanoma no significant therapeutic benefit was observed by adding the anti-estrogen tamoxifen to polychemotherapy
MMMP State
uncharacterized
MMMP Molecule
Estrogen receptor
MMMP Molecule Alias
ESR1
MMMP Relationship
no relationship with
MMMP Drug
Cisplatin + Dacarbazine + Carmustine
MMMP Model
6
MMMP Reference
Creagan ET, J Clin Oncol 1999, 17:1884-90
Drugs
Drug NameSensitivitySupported
Cisplatin + Dacarbazine + Carmustine Resitance or Non-Reponsetrue