Annotation Detail
Information
- Associated Genes
- TNFRSF9
- Associated Variants
- TNFRSF9 OVEREXPRESSION
- Source Database
- MMMP
- Description
- The combination of the two mAbs, agonistic anti-4-1BB and depleting anti-CD4, results in enhanced antimelanoma activity
- MMMP State
- activated by
- MMMP Molecule
- CD137
- MMMP Molecule Alias
- 4-1BB
- MMMP Modifier
- 4-1BB antibody (agonist)
- MMMP Modifier Alias
- CD137 antibody (agonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CD4+ cell depletion
- MMMP Model
- 2
- MMMP Reference
- Choi BK, Cancer Res 2007, 67:8891-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CD4+ cell depletion | Sensitivity | true |