Annotation Detail
Information
- Associated Genes
- IKBKB
- Associated Variants
- IKBKB UNDEREXPRESSION
- Source Database
- MMMP
- Description
- BMS-345541 is an IKKB inhibitor and thus a NFkB inhibitor (IKKB inhibits IKB, which in turn inhibits NFkB)
- MMMP State
- inhibited by
- MMMP Molecule
- IKKB
- MMMP Molecule Alias
- IKB kinase beta
- MMMP Modifier
- BMS-345541
- MMMP Modifier Alias
- NFkB inhibitor
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 4
- MMMP Reference
- Yang J, Mol Cancer Ther 2009, 8:636-47
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Sensitivity | true |