Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
TLR2 UNDEREXPRESSION
Source Database
MMMP
Description
Combining the TLR2 Ab and chemotherapeutic agent GC significantly improved the therapeutic efficacy of treating the pulmonary metastasis of B16 cells and the survival rate of tumor-bearing mice compared to mice treated with GC alone
MMMP State
inhibited by
MMMP Molecule
TLR2
MMMP Molecule Alias
Toll like receptor 2
MMMP Modifier
TLR2 antibody (antagonist)
MMMP Relationship
sensitivity to
MMMP Drug
Gemcitabine
MMMP Model
2
MMMP Reference
Yang HZ, PLoS One 2009, 4:e6520
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
GemcitabineSensitivitytrue