Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- This study showed enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824 (melanoma cells used for the challenge were previously treated with LAQ824)
- MMMP State
- inhibited by
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Modifier
- LAQ824
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Adoptive cell therapy (immunotherapy)
- MMMP Model
- 2
- MMMP Reference
- Vo DD, Cancer Res 2009, 69:8693-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Adoptive cell therapy (immunotherapy) | Sensitivity | true |