Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- CTLA4 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- The combination therapy induced tumor rejection and skin depigmentation in B cell-deficient and in CD4(+) T cell-depleted mice. Both effects of the treatment absolutely required CD8(+) T cells
- MMMP State
- inhibited by
- MMMP Molecule
- CTLA4
- MMMP Modifier
- CTLA4 antibody (antagonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Vaccine (GMCSF producing tumor cells)
- MMMP Model
- 2
- MMMP Reference
- van Elsas A, J Exp Med 2001, 194:481-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Vaccine (GMCSF producing tumor cells) | Sensitivity | true |