Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- CTLA4 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- CD25 antibody leads to depletion of CD25+ Treg cells (immunosuppressive cells). CTLA4: co-inhibitory molecule
- MMMP State
- inhibited by
- MMMP Molecule
- CTLA4
- MMMP Modifier
- CTLA4 antibody (antagonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CD25 antibody (antagonist)
- MMMP Model
- 2
- MMMP Reference
- Sutmuller RP, J Exp Med 2001, 194:823-32
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CD25 antibody (antagonist) | Sensitivity | true |