Annotation Detail
Information
- Associated Genes
- H2AX
- Associated Variants
- H2AX UNKNOWN
- Source Database
- MMMP
- Description
- Dbait is a small molecule mimicking DNA damage (it causes H2AX phosphorylation) that inhibits DNA repair and thus sensitizes to radiotherapy
- MMMP State
- phosphorylated
- MMMP Molecule
- H2AX
- MMMP Modifier
- Dbait
- MMMP Modifier Alias
- DNA damage mimic
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Radiotherapy
- MMMP Model
- 4
- MMMP Reference
- Quanz M, Clin Cancer Res 2009, 15:1308-16
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Radiotherapy | Sensitivity | true |