Annotation Detail

Information
Associated Genes
HDAC9
Associated Variants
HDAC9 UNDEREXPRESSION
Source Database
MMMP
Description
HDAC inhibitors radiosensitize human tumor cells by affecting their ability to repair the DNA damage induced by ionizing radiation (gamma-H2AX phosphorylation could be used as a predictive marker of radioresponse)
MMMP State
inhibited by
MMMP Molecule
HDAC
MMMP Molecule Alias
Histone deacetylase
MMMP Modifier
Butyric acid
MMMP Modifier Alias
HDAC inhibitor
MMMP Relationship
sensitivity to
MMMP Drug
Radiotherapy
MMMP Model
3
MMMP Reference
Munshi A, Clin Cancer Res 2005, 11:4912-22
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
RadiotherapySensitivitytrue