Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- HDAC inhibitors radiosensitize human tumor cells by affecting their ability to repair the DNA damage induced by ionizing radiation (gamma-H2AX phosphorylation could be used as a predictive marker of radioresponse)
- MMMP State
- inhibited by
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Modifier
- Butyric acid
- MMMP Modifier Alias
- HDAC inhibitor
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Radiotherapy
- MMMP Model
- 3
- MMMP Reference
- Munshi A, Clin Cancer Res 2005, 11:4912-22
- MMMP DNA/mRNA/Protein
- protein
Drugs
Drug Name | Sensitivity | Supported |
---|---|---|
Radiotherapy | Sensitivity | true |