Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Rac1/JNK activation is critical for cell cycle arrest and apoptosis induction by plitidepsin (a marine depsipeptide) in melanoma cells
- MMMP State
- inhibited by
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Modifier
- Plitidepsin
- MMMP Modifier Alias
- Aplidin
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Dacarbazine
- MMMP Drug Alias
- DTIC
- MMMP Model
- 3
- MMMP Reference
- Munoz-Alonso MJ, J Pharmacol Exp Ther 2008, 324:1093-101
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Dacarbazine | Sensitivity | true |