Annotation Detail
Information
- Associated Genes
- STAT3
- Associated Variants
- STAT3 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- CpG oligonucleotide: TLR9 agonist. STAT3 activation in tumor and dendritic cells (DC) are believed to contribute to intra-tumoral immunosuppressive environment
- MMMP State
- inhibited by
- MMMP Molecule
- STAT3
- MMMP Molecule Alias
- Signal transducer and activator of transcription 3
- MMMP Modifier
- JSI-124
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CpG oligonucleotide
- MMMP Model
- 2
- MMMP Reference
- Molavi O, Immunol Cell Biol 2008, 86:506-14
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CpG oligonucleotide | Sensitivity | true |