Annotation Detail
Information
- Associated Genes
- PRRT2
- Associated Variants
- PRRT2 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- The exposure of human melanoma BRO cells in culture simultaneously with cisplatin (1-10 microM) and PNAE(s) (100 microM-1 mM) in a molar ratio of 1/100 for 24 h induced a considerable decrease in the ability of these cells to incorporate [3H]thymidine into DNA. A considerable antiproliferative synergism of these agents was observed
- MMMP State
- inhibited by
- MMMP Molecule
- PKC
- MMMP Molecule Alias
- Protein kinase C
- MMMP Modifier
- PNAE
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 3
- MMMP Reference
- Mikhaevich IS, Anticancer Drugs 1992, 3:513-7
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | Sensitivity | true |