Annotation Detail
Information
- Associated Genes
- HMGCR
- Associated Variants
- HMGCR UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Co-administration of isoprenoids (vitamin E isomers with an isoprenoid moiety) that posttranscriptionally down-regulate tumor reductase may lower the effective dose of statins necessary for antimelanoma activity
- MMMP State
- inhibited by
- MMMP Molecule
- HMG CoA reductase
- MMMP Molecule Alias
- HMGCR
- MMMP Modifier
- Lovastatin
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Tocotrienol
- MMMP Model
- 2
- MMMP Reference
- McAnallys JA, Exp Biol Med 2007, 232:523-31
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Tocotrienol | Sensitivity | true |