Annotation Detail
Information
- Associated Genes
- MARCO
- Associated Variants
- MARCO UNDEREXPRESSION
- Source Database
- MMMP
- Description
- In vivo, anti-MARCO antibody treated tumor lysate-pulsed dendritic cells showed better trafficking from the skin injection site to lymph node, enhanced generation of tumor-reactive IFN-gamma producing T cells, and improved therapeutic efficacy against B16 melanoma
- MMMP State
- inhibited by
- MMMP Molecule
- MARCO
- MMMP Modifier
- MARCO antibody (antagonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Vaccine (dendritic cells)
- MMMP Model
- 2
- MMMP Reference
- Matsushita N, Cancer Immunol Immunother 2010, Epub ahead of print
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Vaccine (dendritic cells) | Sensitivity | true |