Annotation Detail
Information
- Associated Genes
- MAP2K7
- Associated Variants
- MAP2K7 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- 219476: CDK4 inhibitor. Investigators examined the effect of cotargeting both pathways with MEK inhibitor PD98059 and CDK4 inhibitor 219476 on human melanoma cells lines, and found that combinatorial treatment dramatically increased apoptosis compared to the single agent treatment
- MMMP State
- inhibited by
- MMMP Molecule
- MEK
- MMMP Modifier
- PD98059
- MMMP Modifier Alias
- MEK inhibitor
- MMMP Relationship
- sensitivity to
- MMMP Drug
- 219476
- MMMP Drug Alias
- CDK4 inhibitor
- MMMP Model
- 3
- MMMP Reference
- Li J, Cancer Invest 2009, Epub ahead of print
- MMMP DNA/mRNA/Protein
- protein
Drugs