Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 UNDEREXPRESSION
Source Database
MMMP
Description
T22 acts as an antagonist of CXCR4, whose natural ligand is CXCL12
MMMP State
inhibited by
MMMP Molecule
CXCR4
MMMP Modifier
T22 peptide antagonist
MMMP Relationship
sensitivity to
MMMP Drug
Cyclophosphamide
MMMP Drug Alias
CTX
MMMP Model
2
MMMP Reference
Lee CH, Mol Cancer Ther 2006, 5:2592-9
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
CyclophosphamideSensitivitytrue