Annotation Detail
Information
- Associated Genes
- CXCR4
- Associated Variants
- CXCR4 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- T22 acts as an antagonist of CXCR4, whose natural ligand is CXCL12
- MMMP State
- inhibited by
- MMMP Molecule
- CXCR4
- MMMP Modifier
- T22 peptide antagonist
- MMMP Relationship
- sensitivity to
- MMMP Drug
- CTLA4 antibody (antagonist)
- MMMP Model
- 2
- MMMP Reference
- Lee CH, Mol Cancer Ther 2006, 5:2592-9
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| CTLA4 antibody (antagonist) | Sensitivity | true |