Annotation Detail

Information
Associated Genes
CD4
Associated Variants
CD4 UNDEREXPRESSION
Source Database
MMMP
Description
Partial CD4 depletion reduces regulatory T cells induced by multiple vaccinations and restores therapeutic efficacy of adoptive cell transfer
MMMP State
inhibited by
MMMP Molecule
CD4
MMMP Modifier
CD4 antibody (antagonist)
MMMP Relationship
sensitivity to
MMMP Drug
Adoptive cell therapy (immunotherapy)
MMMP Model
2
MMMP Reference
Lacelle MG, Clin Cancer Res 2009, 15:6881-90
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
Adoptive cell therapy (immunotherapy)Sensitivitytrue