Annotation Detail
Information
- Associated Genes
- XIAP
- Associated Variants
- XIAP UNDEREXPRESSION
- Source Database
- MMMP
- Description
- The X-linked inhibitor of apoptosis protein (XIAP) is upregulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization
- MMMP State
- inhibited by
- MMMP Molecule
- XIAP
- MMMP Modifier
- Phenoxodiol
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Carboplatin
- MMMP Model
- 3
- MMMP Reference
- Kluger HM, J Transl Med 2007, 5:6
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Carboplatin | Sensitivity | true |