Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
- ABCB1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- HM30181A: P-gp inhibitor. P-gp in the brain microenvironment has crucial roles in the brain metastatic tumor chemoresistance: P-gp inhibitor HM30181A treatment should be considered in the development of brain endothelial cell-targeted chemotherapy
- MMMP State
- inhibited by
- MMMP Molecule
- ABCB1
- MMMP Molecule Alias
- MDR1, P-gp
- MMMP Modifier
- HM30181A
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Paclitaxel
- MMMP Drug Alias
- Taxol
- MMMP Model
- 2
- MMMP Reference
- Joo KM, Int J Oncol 2008, 33:705-12
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Paclitaxel | Sensitivity | true |