Annotation Detail
Information
- Associated Genes
- IGF1R
- Associated Variants
- IGF1R UNDEREXPRESSION
- Source Database
- MMMP
- Description
- MFG-E8: Milk fat globule EGF-8. MFG-E8 augments melanoma cell resistance to apoptosis, triggers an epithelial-to-mesenchymal transition (EMT) and stimulates immune suppression
- MMMP State
- inhibited by
- MMMP Molecule
- IGF1R
- MMMP Molecule Alias
- IGF1 receptor
- MMMP Modifier
- AG538
- MMMP Relationship
- sensitivity to
- MMMP Drug
- MFG-E8 siRNA
- MMMP Model
- 3
- MMMP Reference
- Jinushi M, Cancer Res 2008, 68:8889-98
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| MFG-E8 siRNA | Sensitivity | true |