Annotation Detail
Information
- Associated Genes
- S100A2
- Associated Variants
- S100A2 OVEREXPRESSION
- Source Database
- MMMP
- Description
- Uveal melanoma. Decitabine upregulates S100A2 (a putative tumor suppressor) expression and synergizes with IFN-gamma to kill uveal melanoma cells
- MMMP State
- upregulated by
- MMMP Molecule
- S100A2
- MMMP Modifier
- Decitabine
- MMMP Modifier Alias
- 5-aza-2'-deoxycytidine
- MMMP Relationship
- sensitivity to
- MMMP Drug
- IFN gamma
- MMMP Model
- 3
- MMMP Reference
- Gollob JA, Clin Cancer Res 2007, 13:5219-25
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| IFN gamma | Sensitivity | true |