Annotation Detail
Information
- Associated Genes
- HDAC9
- Associated Variants
- HDAC9 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- A combination of retinoic acid (RA) and HDACI acted synergistically to activate RA signaling and inhibit tumor growth. These experiments identify the RA pathway as a rate-limiting target of HDACI and suggest strategies to enhance the therapeutic efficacy of HDACI
- MMMP State
- inhibited by
- MMMP Molecule
- HDAC
- MMMP Molecule Alias
- Histone deacetylase
- MMMP Modifier
- PXD101
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Retinoic acid
- MMMP Drug Alias
- 13-cis retinoic acid
- MMMP Model
- 4
- MMMP Reference
- Epping MT, Proc Natl Acad Sci USA 2007, 104:17777-82
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Retinoic acid | Sensitivity | true |